{"id":1521,"date":"2020-08-14T13:16:48","date_gmt":"2020-08-14T16:16:48","guid":{"rendered":"https:\/\/edctecnologia.com.br\/computational-fluid-dynamics-morphological-and-hemodynamic-changes-in-abdominal-aortic-aneurysm\/"},"modified":"2020-08-28T01:04:10","modified_gmt":"2020-08-28T04:04:10","slug":"computational-fluid-dynamics-morphological-and-hemodynamic-changes-in-abdominal-aortic-aneurysm","status":"publish","type":"post","link":"https:\/\/edctecnologia.com.br\/es\/computational-fluid-dynamics-morphological-and-hemodynamic-changes-in-abdominal-aortic-aneurysm\/","title":{"rendered":"Computational fluid dynamics: morphological and hemodynamic changes in abdominal aortic aneurysm"},"content":{"rendered":"
Objectives:<\/strong> The purpose of this study was to demonstrate qualitatively and quantitatively the morphological and hemodynamic changes in<\/p>\n abdominal aortic aneurysm (AAA), in order to find predictor factors of progression and of rupture of AAA compared with healthy aorta, based on<\/p>\n multidetector CT (MDCT) datasets using the possibilities of Computational Fluid Dynamics (CFD).<\/p>\n Materials and Methods:<\/strong> 30 patients with AAA (diameter\u226540mm, age = 62\u00b114 years) and 30 patients with healthy aorta (age 51\u00b112 years)<\/p>\n underwent MDCT. The aortic lumen was extracted by means of semi-automatic segmentation process with dicom viewer interface (Osirix, Pixmeo,<\/p>\n Switzerland). The fluid was solved with Lattice Bolzmann Method as Newtonian incompressible particles fluid with pulsting flow (Xflow, Next Limits<\/p>\n technologies, Madrid). Diameters, volumes, blood flow velocities, regional wall shear stress (WSS) were quantified. Statistics..<\/p>\n Results:<\/strong> The AAA maximum diameter and thrombus volume positively correlated to time to peak systolic velocities (r=0,6 ;0,5) and inversely<\/p>\n correlated to peak systolic WSS(r=0,4;0,6) The peak systolic WSS in the abdominal aorta of AAA patients was lower significantly than normal aorta<\/p>\n group (p<0.01) Peak WSS (Pa) of proximal neck, aneurismal sac, and distal neck were 0,38; 0,15; 0,31 respectively. In infrarenal abdominal aorta,<\/p>\n WSS of posterior wall (0,17Pa) was always lower than anterior wall (0,22Pa). Maximum acceleration and deceleration of velocity were found highest<\/p>\n at the suprarenal abdominal aorta for two group patient.<\/p>\n Conclusion:<\/strong> Increase in AAA maximum diameter and thrombus volume is significantly correlated with the decrease in systolic WSS. CFD provide<\/p>\n better predictors of aortic rupture risk. Our method can be used routinely in clinical practice.<\/p>\n <\/p>\n